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Jean-Marie Bassett, born in the London area, is half-British/half-French, but now living in The Netherlands, (so fairly European), graduated in Chemistry at London University. He took his PhD at Bristol University in Organometallic Chemistry and completed his academic career in organometallics at the Technical University Munich with a Royal Society European Fellowship, followed by the City University London, before joining Royal Dutch Shell Research in Amsterdam. Combining the qualities of a scientific education and business instincts, Jean-Marie embarked on a career in business development and product management for Fine Chemicals and Specialities at Shell, Boehringer Mannheim, FRP Services and Helm before finally joining TNO in Delft. At TNO, the Dutch Applied Research organisation, he has been active in setting up the business in innovative technologies for chemicals processing. Jean-Marie has published about 20 articles in organometallics and later in technology development. For relaxation Jean-Marie plays golf, reads medieval history and plays the piano when nobody is around!

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Jean-Marie Bassett

C. Oliver Kappe

Professor C. Oliver Kappe received his diploma- (1989) and doctoral (1992) degrees in organic chemistry from the University of Graz where he worked with Professor Gert Kollenz on cycloaddition and rearrangement reactions of acylketenes. After periods of postdoctoral research work on reactive intermediates and matrix isolation spectroscopy with Curt Wentrup at the University of Queensland in Brisbane, Australia (1993-1994) and on synthetic methodology/alkaloid synthesis with Albert Padwa at Emory University in Atlanta, USA (1994-1996), he moved back to the University of Graz in 1996 to start his independent academic career. He obtained his “Habilitation” in 1998 in organic chemistry and was appointed Associate Professor in 1999. From 2011-2016 he held the position of Professor of “Technology of Organic Synthesis” (Organische Synthesetechnologie) at the University of Graz. He currently is Key Researcher at the Research Center Pharmaceutical Engineering (RCPE) in Graz.

The co-author of ca. 350 publications, his main research interest for the past 10 years focused on enabling and process intensification technologies in synthetic organic chemistry, in particular on the continuous generation of Active Pharmaceutical Ingredients (APIs). From 2010 he has been Editor-in-Chief of the Journal of Flow Chemistry and a Board Member of the Flow Chemistry Society.

Christoph Aellig, Ph.D., joined Lonza Visp as project leader in 2015. Currently, his work focuses on microreactor technology for the continuous manufacturing of pharmaceutical compounds.

 

After receiving his M.Sc. in Chemical- and Bioengineering from ETH Zurich (Switzerland, 2009), Christof Aellig obtained a Ph.D. under the supervision of Prof. Dr. Ive Hermans. His thesis focused on selective aerobic alcohol oxidations mediated by nitric acid. Christoph completed his post-doc with Prof. Dr. Ive Hermans and Prof. Dr. Javier Pérez-Ramírez at ETH Zurich.

Christoph Aellig

Jesús Alcázar studied in Universidad de Castilla-La Mancha in Ciudad Real where he got his bachelor degree in 1990 and Ph. D. in 1996. As Ph. D. student he stayed for 6 months at the Royal Danish School of Pharmacy (Copenhagen, Denmark) under the direction of Prof. Michael Begtrup.  In 1995 he joined Janssen-Cilag at the research center in Toledo. Currently he is Senior Principal Scientist at Janssen Research and Development. In this position he is involved in the implementation of novel technologies in Drug Discovery in Toledo and in collaboration with other J&J sites worldwide. In this role he has led the successful implementation of 3 different technologies: microwave, H-CUBE and Flow chemistry. From this work he has been author of more than 45 articles, 4 reviews and 3 book chapters. In addition he has successfully applied these technologies to Medicinal Chemistry programs with 4 compounds selected as clinical candidates. This part of the work is reflected as inventor in more than 25 patent applications. He has also been invited speaker in more than 10 international symposiums.

Jesus Alcazar

Arne Askildsen holds a Master degree in Biotechnology from the Technical University of Trondheim (NTH, today NTNU) from 1987. He joined the Innovation and Development Department at Lindesnes in Nycomed (a part of GE Healthcare since 2004) in 1996.

Arne works as a Senior Adviser in Industrial Process Technology. He has extensive experience in process development, process design and process technologies and has been a pioneer at Lindesnes in process intensification and continuous technologies.

Arne Askildsen

I got the degree in “Chimica Industriale” at the University of Turin in 1986. I joined “3M Reseach Italy” in 1988, Ferrania site, working as researcher in the Organic Synthesis Laboratory about imaging chemicals. I worked in the Chemical Area up to March 2011, and I left the company as responsible of the Production, Research&Development and Sales of fine chemicals. I joined la Mesta in April 2011 and I am working in the Innovation and Commercial Area.

Massimo Bertoldi

Wim Dermaut obtained his Ph.D. in physical organic chemistry at the Structural Chemistry group of the University of Antwerp in 2002. He then joined Janssen Pharmaceutica (Johnson & Johnson) where he worked in the Process Safety Lab for 6 years and in the Preparative Chromatography Group for 3 years. In 2011 he joined Agfa as an R&D manager, focusing on process development and scale up, safety testing and technology scouting. Since 2014, he is the project manager of the “Atom” project, a funded research consortium between academia and industry, aiming at the development of a flow chemistry community in Flanders.

 

 

Wim Dermaut

Bertrand Gallet

After being graduated from the French Engineer School of CPE Lyon and the University of Würzburg (Germany) in Chemistry, Bertrand Gallet stepped in the ion exchange technology by working in the technical departments of Dow Chemical and Purolite. Part of the projects involved evaluation of new product performance, engineering support and help to troubleshooting.

In 2013, he joined the commercial team of Purolite and focus on technical sales, to develop new applications and to follow major accounts.

In 2016, he joined Corning to support the sales growth of the Advanced-Flow Reactor in Europe (AFR).

His main activities consist in extending the Corning network, to develop the application of the Advanced-Flow Reactor business for customers and to promote the AFR technology in Europe.

Viktor Gyollai

He was born and graduated in Hungary, earned his Ph.D. at the University of Debrecen in the field of carbohydrate chemistry in 2001. Started his industrial career at TEVA Pharmaceuticals as a project leader at Synthetic R&D where he became the co-author of 8 patents on the synthesis and characterisation of generic drug molecules and their polymorphic forms till the end of 2006.

In 2007, he joined the research group of Prof. Licheng Sun at Royal Technical University in Stockholm to synthesise Mn- , Ru- and Iridium-based complexes as potential catalysts for the catalytical oxidation of water to oxygen.

He moved back to Hungary in 2009 and joined Thalesnano as a Senior Flow Chemist. Later he became the Head of Chemistry. He was involved in almost all chemical and instrument development projects, gave presentations on conferences and customers’ sites.

He was offered the position of Head of Continuous Technologies at Ubichem Pharma Group in 2012 to investigate a number of different types of flow processes.

In October 2014, he joined AM Technology to become the Head of Chemical Laboratories.

Bashir Harji

Bashir Harji is an Asian who arrived in the UK as a refugee in 1972, aged 12.  He graduated in London and followed this by taking a PhD in Cambridge with Dr. Mary Archer.  He has six year of postdoctoral experience at the Department of Chemical Engineering also in Cambridge.  He started Cambridge Reactor Design (CRD) with his good friend Dr. Nigel Kenney in 1989.  He has run this company for over 25 years.  Today, CRD is a provider of Scientific Instruments worldwide.  Bashir passionately believes in a UK manufacturing base and flow chemistry is one area of his expertise. He has about twenty patents to his name; CRD provides goods and services to some of the biggest companies in the world.  Favorite saying, “I have not failed, but found 1000 ways to not make a light bulb”, Thomas Edison.

Peter Hermsen

Peter Hermsen has been working in the field of process R&D for over 17 years. After obtaining his PhD from the University of Nijmegen, The Netherlands, he joined the development group of DSM Pharma Chemicals, where he was active in the scale-up, implementation and optimization of fine chemical processes. In 2005, he was appointed Senior Scientist at DSM Research, where he was involved in numerous and diverse route scouting projects, for both internal and external customers. As of May 2017, he continues this role within InnoSyn BV.

Gareth Jenkins

Dr Gareth Jenkins is the Chief Executive Officer for Britest Limited, a global leader in the development of innovative process design solutions for the chemical and chemistry-using processing sector. Britest collaborates with chemical companies to help them improve their approach to process development and identification of manufacturing improvements. The Britest Toolkit has generated more than a billion pounds of lasting operating value over the last 20 years for the businesses that have embedded the Britest Approach into their day to day activities. Previously the Chief Operating Officer for AM Technology, a chemistry engineering company developing innovative flow reactors and VP for Process Research & Development at AMRI / Excelsyn’s North Wales chemical development and small-scale manufacturing site, Gareth has focused on strategic research and business development roles. He gained his PhD at Imperial College London in Organic Chemistry and has an MBA in Entrepreneurship from Manchester Business School. He is currently the Chairman of the Royal Society of Chemistry Speciality Chemicals Sector and an active member of Innovate UK’s Chemistry Innovation Strategy Board and the European SPIRE public-private partnership.

gareth.jenkins@britest.co.uk  |  www.britest.co.uk

Britest Limited, The Innovation Centre, Daresbury Sci-Tech, Keckwick Lane, Daresbury, WA4 4FS, UK

Anne Kaaden studied business chemistry at the Christian Albrechts Universität in Kiel and started her career in the area of continuous flow in 2012 for Ehrfeld Mikrotechnik BTS. As a global Key Account Manager and Head of Marketing her important fields of activity are lying in preparation of workshops, commissioning of equipment and organizing fairs and conferences. One favourite activity of Anne Kaaden is giving lectures and training sessions for this new technology platform of micro- and millireactors.

Anne Kaaden

Walter Linhart, born 1977, studied chemical engineering at the Graz University of Technology. He finished his studies in 2005 and joined Microinnova in 2003.

In 2005 he was promoted to the head of engineering. In this role he executed several realization projects of continuous pilot and production plants for the pharmaceutical industry, the fine chemical industry and research centers as project manager. He has held the position of Microinnova’s project leader in three EU research projects in the 7th framework program.

Walter Linhart has a certificate for ‘GMP expert plant qualification’ and a special education in explosion protection and project management. In May 2017 he retired as head of engineering and took on the position of head of marketing and sales.

Since 2006 he is shareholder of Microinnova Engineering GmbH and has been promoted to an Authorized Officer in 2014.

Walter Linhart

I have earned a master’s degree in chemical engineering from Nagoya University, Japan, in 2008. After assigning to the current position at Technical Development Group, Kobe Steel, LTD., I worked for the development of the pressure swing adsorption system for carbon monoxide separation from combustion exhaust gas in iron making plants and petrochemical plants from 2008 to 2011. I am joining to the research and development for micro chemical process technologies from 2011 to present. My current tasks are to establish the methodology for device and process designs of multichannel large capacity micro channel reactor and to develop the applications of our device, stacked multi-channel reactor (SMCR®), for bulk chemical industries.

Akira Matsuoka

Dr. D. Tyler McQuade, Professor of Chemical and Life Science Engineering at Virginia Commonwealth University, has a background in flow chemistry and catalysis. Dr. McQuade published over 80 manuscripts (H-Factor = 33), patents and book chapters on topics ranging from catalysis to macromolecules to pharmaceutical agent synthesis. Dr. McQuade started the Medicines for All Initiative with his close colleague Professor Frank Gupton. This Bill & Melinda Gates Foundation funded initiative has reduced production costs of a variety of anti-viral compounds such as nevirapine. Dr. McQuade has had a wide range of professional experiences including program manager and later the deputy director of DARPA’s Defense Sciences Office (DSO), a visiting group leader at the Max Planck Institute of Colloids and Interfaces and a visiting professor in the Food and Nutrition Toxicology Department at the ETH-Zurich. Dr. McQuade received a PhD degree in Chemistry from the University of Wisconsin and a BS in Chemistry and BS in Biology from UC Irvine. He was a NIH Post-Doctoral Fellow at MIT prior to starting his independent research career.

Tyler McQuade

Roger-Marc Nicoud holds a PhD from University of Lorraine in process simulation for the nuclear industry. He joined Separex in 1987, first as a Technical Director and then as a Managing Director until 1995. Between 1993 and 1995, he also occupied a position of Professor and Head of a research laboratory involved in thermodynamics at the University of Lorraine. Roger-Marc Nicoud founded Novasep in 1995 with the vision to develop comprehensive solutions for the production of bio- and synthetic molecules. Novasep became a leader serving the life sciences industry with a recognized portfolio of innovative technologies. He held the position of CEO of Novasep until October 2012, and Chairman of the Novasep Supervisory Board until February 2014. Roger-Marc Nicoud founded Ypso-Facto in 2014 as a service company offering assistance to industrial firms to develop, optimize and secure their chemical and bioprocesses. He has published the book Chromatographic processes: modeling, simulation and design1 in 2015.

 

1Chromatographic Processes - Modeling, Simulation, and Design, Roger-Marc Nicoud, 672 pages, Cambridge University Press, Cambridge Series in Chemical Engineering, New-York (2015), ISBN: 9781107082366

Roger-Marc Nicoud

Peter Poechlauer received a PhD in organic chemistry from Innsbruck University in 1986.

2 years of post-doc studies at Munich University in the Laboratories of Prof. Rolf Huisgen  followed. Both activities were dedicated to the elucidation of organic reaction pathways.

In 1990 he joined Chemie Linz, later OMV, as a synthetic chemist.

Since 1996 he has worked with DSM as scientist, project leader and competence manager. Focal areas: biocatalysis and oxidation chemistry.

2003 – 2007 he headed a department of process technology.

Since 2007 he has worked as principal scientist with a focus on process intensification and micro reactor technology.

Since 2014 with the formation of DPx/Patheon he has been responsible for Innovation Management.

Peter Poechlauer

Alain RABION graduated as a Chemical Engineer from the French engineer school of “Chimie-Physique Bordeaux” and obtained his PhD in Organic chemistry at University of Bordeaux. After a Post-doc in biomimetic domain at Lawrence Berkeley laboratory, CA (Dr Fish group), Alain started his industrial career, in 1995, at Elf Atochem Research Center in LACQ (FRANCE) as R&D Laboratory HEAD.

In 2000, Alain joined Sanofi group and held different positions in Chemical Development, developing scientific expertise in process design, process development, scale-up methodology, safety testing and manufacture at pilot plant.

Since 2014, Alain has joined the Science and Innovation department as Global Function Head in Chemistry for Process Development teams. In this role, he has been active in implementing new reaction conditions and innovative technologies for chemical processing. As a Sanofi representative within IMI chem21 consortium (2012-2017), he has been working on several innovative reactions/technologies including fluorination and flow chemistry, in collaboration with other European partners.

Alain Rabion

Rudi Oliveira holds a degree in Pharmaceutical Sciences and a PhD in Medicinal Chemistry, with a strong component on organic chemistry. He also worked as a PostDoc in Chemical Biology before joining Hovione in 2015 as a chemist in the Continuous Manufacturing group. Here he was responsible for gathering knowledge on flow chemistry and conduce process development work of continuous processes with view to industrialization. Recently, he was integrated in the Process Chemistry Development group to combine both knowledge in batch and flow chemistry.

Rudi Oliveira

Starting his career in 2003 at A. Hak Industrial Services, he moved in 2004 to Octoplus in Leiden to work on the process development of controlled release devices. In 2008, Wouter co-founded Flowid BV (a spin out of the Eindhoven University of Technology) as Managing Director.

My role within Flowid is financial and commercial management of Flowid. My added value is to combine people and their expertise in combination with a thorough analysis of the problem. To realize together a more efficient process industry.

Flowid is leader in continuous process solutions. From process development services to the engineering and construction of skids. ​Flowid manufacturers SpinPro reactors for lab, development and production scale. SpinPro reactors have excellent mass and heat transfer. Flowid​'​s technology provides unique control of exothermic multiphase reactions, precipitation and emulsification purposes.

Wouter Stam

Flavien Susanne graduated in 2001 with a Master degree in Engineering and in 2003 from a Chemical Engineering degree from the University of Normandy, France.

In 2004, Flavien joined Pfizer UK, working in the R&D department. In 2006, he joined the new continuous process development team, leading the development of the first Pfizer end to end flow process.

In 2011, Flavien joined Novartis Switzerland, working in the Continuous Manufacturing Unit, leading the development of flow process development and the implementation in GMP facilities.

In 2014, Flavien joined GSK leading the continuous process engineering team.

Flavien has been really active with the academia in all these years working closely with CMAC and MIT for the development of new methodology and technology for flow processing.

Flavien Suzanne

John Tsanaktsidis

Dr Tsanaktsidis is a Research Director at CSIRO Manufacturing. He applies his extensive background and experience in scientific research, management, business development, technology commercialisation, and business leadership to deliver commercial value through the creation and translation of innovative technical solutions to the chemical manufacturing industry.

He is a Fellow of the RACI and Chair of the Organic Chemistry Division of the RACI, the peak body for chemists in Australia.

Dr Tsanaktsidis is an experienced synthetic organic chemist focused on the development and translation of chemistry solutions to the chemical industry. He has the ability to build rapport with colleagues, collaborators, and customers, and has demonstrated an ability to deliver on complex industrial and multidisciplinary projects. In recent years Dr Tsanaktsidis has led the establishment Australia’s first continuous flow processing (flow chemistry) laboratory at CSIRO Manufacturing, for the sustainable and efficient production of commercially important fine chemicals, polymers, and pharmaceuticals. This cutting edge laboratory represents radical paradigm shift in the field of chemical manufacturing.

Dr Tsanaktsidis has authored or co-authored over 60 peer reviewed papers, patents, and book chapters, and has an h-index of 15. His efforts have been recognised by CSIRO for Business Excellence (2003) and Project Management (2004), and through a Chief's Innovation Award for his efforts in continuous flow chemistry (2012), and by The Flinders University of South Australia in 2006 through a Distinguished Alumni Award.

Charlotte Wiles

Chief Executive Officer, Chemtrix BV, Chemelot Campus, Gate 2, Urmonderbaan 22, 6167 RD, Geleen, The Netherlands, c.wiles@chemtrix.com

 

Starting her research in the area of continuous flow synthesis in 2000, Charlotte obtained her PhD in 2003 entitled ‘Microreactors in Organic Synthesis’ from the University of Hull (UK). This was followed by 5 years of Post-Doctoral research into the rapidly developing field of continuous flow synthesis, specifically in the area of small molecule synthesis.

In 2008, Charlotte joined Chemtrix BV (a spin out of the University of Hull) as a Senior Chemist where she worked on the commercialisation of lab-scale micro reactor apparatus, followed by the development of scale up strategies to access kilo-scale production. In 2010 she was promoted to Chief Technology Officer within Chemtrix BV and in August 2013 to CEO, where she continues to research and develop continuous flow systems and solutions for both industrial and academic partners. More recent developments have focused on the development of advanced industrial flow reactors, suited towards the development of flexible tonne-scale production plants, performed in cooperation with 3M Germany.